One major thrust in radiology today is image standardization with a focus on rapidly acquired quantitative multi-contrast information. In this paper, we discuss the strengths and weaknesses of STAGE, demonstrate its contrast-to-noise (CNR) behavior relative to a large clinical data…
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Strategically acquired gradient echo (STAGE)-derived MR angiography might be a superior alternative method to time-of-flight MR angiography in visualization of leptomeningeal collaterals
This study aimed to compare the performance of strategically acquired gradient echo (STAGE)-derived MR angiography and time-of-flight MR angiography (TOF-MRA) in visualization of leptomeningeal collaterals (LMCs).
Quantitative Susceptibility Mapping for Characterization of Intraplaque Hemorrhage and Calcification in Carotid Atherosclerotic Disease
Carotid artery intraplaque hemorrhage (IPH), an unstable component of atherosclerosis, is associated with an increased risk of stroke. This prospective study aims to investigate the use of quantitative susceptibility mapping (QSM) as a tool for the evaluation of IPH and…
Plaque characteristics of middle cerebral artery assessed using strategically acquired gradient echo (STAGE) and vessel wall MR contribute to misery downstream perfusion in patients with intracranial atherosclerosis
To assess plaque vulnerability of the middle cerebral artery (MCA) using strategically acquired gradient echo (STAGE) versus high-resolution vessel wall MRI (hr-vwMRI), and explore the relationship between plaque characteristics and misery downstream perfusion.
Intracranial iron distribution and quantification in aceruloplasminemia: A case study
Aceruloplasminemia (ACP) is a rare autosomal recessive disorder characterized by intracranial and visceral iron overload. The aim of this study was to provide quantitative iron measurements for each affected brain region in an ACP patient with the potential to do…
Neuroimaging for COVID-19
Approximately ⅓ of COVID-19 patients have shown neurological symptoms like headache, an altered mental state, acute cerebrovascular disease, and epilepsy. STAGE can be used to detect vascular damage and hemorrhagic lesions in the brain with greater detail than standard methods…
Clinical applications of STAGE published in the journal Magnetic Resonance Imaging
One major thrust in radiology today is image standardization with a focus on rapidly acquired quantitative multi-contrast information. This is critical for multi-center trials, for the collection of big data and for the use of artificial intelligence in evaluating the data. Strategically acquired gradient echo (STAGE) imaging is one such method that can provide 8… “Clinical applications of STAGE published in the journal Magnetic Resonance Imaging”
Regional High Iron in the Substantia Nigra Differentiates Parkinson’s Disease Patients From Healthy Controls
Iron is important in the pathophysiology of Parkinson’s disease (PD) specifically related to degeneration of the substantia nigra (SN). The goal of this work was to use quantitative susceptibility mapping (QSM) and R2∗ to quantify both global and regional brain…
Quantifying iron content in magnetic resonance imaging
In this work, we review the basic concepts behind imaging iron using T2, T2*, T2′, phase and quantitative susceptibility mapping in the human brain, liver and heart, followed by the applications of in vivo iron quantification in neurodegenerative diseases, iron…
Susceptibility mapping of the dural sinuses and other superficial veins in the brain
In this paper, we propose a method that seeks to reconstruct the susceptibility distribution inside the dural sinuses by ensuring that the entire geometry of the dural sinuses is preserved with the help of an MR angiogram and venogram (MRAV).
