GAIN CLARITY AT SPEED.

Multiple Sclerosis lesions affect the central nervous system and periventricular, peri-venous lesions have been observed throughout the brain and spine. Multiparametric maps from STAGE™ provide enhanced lesion visualization in white matter and heterogeneous changes in blood flow, inflammation, water content, susceptibility and iron deposition, tissue atrophy, demyelination, and abnormal vasculature associated with lesions.

STAGE™ generates highly detailed visualization of trauma-related lesions as well as vascular damage which may be missed by conventional or low-resolution scans. It is particularly useful for accurate depiction of cerebral microbleeds, medullary vascular injury, shearing damage and subarachnoid hemorrhage.

STAGE™ can replace standard, longer-duration GRE and SWI due to its high sensitivity to cerebral microbleeds and thrombus. It also depicts asymmetrically prominent cortical veins, oxygenation in the draining penumbra, focal stroke lesion, angiography flow interruptions and arterial disruption in the Circle of Willis. Standardized STAGE™ outputs also enable baseline and longitudinal image comparisons.

STAGE™ improves visualization and quantification of key areas of interest in the brain including WM/GM contrast and cerebrospinal fluid, neurovascular lesions and hemosiderin deposition, and differentiation of mineralization and hemorrhage. STAGE™ also allows visual determination of dephasing caused by calcification or bleeding. The T1 Map and T1W outputs provide further contrast between tissue types.

STAGE™ provides qualitative and quantitative outputs for visualizing key biomarkers. Multiparametric maps from STAGE™, such as QSM and R2*, quantify the iron content in the deep gray matter structures, visualize neuromelanin in the midbrain and provide automatic segmentation of brain structures. This is especially helpful for earlier detection of disease and for surgical placement of deep brain stimulation (DBS).