The STAGE protocol is designed to be highly sensitive to the visualization of lesions that may originate from trauma. STAGE has the ability to demonstrate key vascular brain damage which may be missed by conventional or low resolution scans…
study
Stroke Detection Use Case
STAGE is designed to benefit imaging and replace standard GRE and SWI in the acute and follow-up setting due to its high sensitivity to blood product lesions in the brain in the form of cerebral microbleeds and thrombus as well as…
Aging & Dementia Use Case
STAGE provides a method to visualize brain tissue and neurovascular changes and lesions in the aging brain and Dementia. Phase data is used to reconstruct the source properties…
Parkinson’s Disease Use Cases
The STAGE protocol can be used to visualize changes in the Neuromelanin and iron content of key dopaminergic structures such as the Pars Compacta located as part of the Substantia Nigra…
Multiple Sclerosis Use Cases
The STAGE protocol helps to provide brain images which help differentiate Multiple Sclerosis lesion properties. The susceptibility-based STAGE outputs help differentiate normal appearing white matter from those which may have become demyelinated…
Tumor Detection, Metastasis & Radiation Therapy Use Case
STAGE helps to provide a robust collection of contrast outputs which can help further differentiate tumor tissue and the changes occurring in surrounding tissue…
Sturge Weber Use Case
STAGE has been utilized to image Sturge Weber in the same way that SWI can be used. In these patients, it is critical to differentiate regions of bleeding versus those that are calcified…
Clinical applications of STAGE published in the journal Magnetic Resonance Imaging
One major thrust in radiology today is image standardization with a focus on rapidly acquired quantitative multi-contrast information. This is critical for multi-center trials, for the collection of big data and for the use of artificial intelligence in evaluating the...
Quantitative MR image processing opens up new avenues of treatment for Traumatic Brain Injury (TBI) in Veterans
For many, the term Traumatic Brain Injury (TBI) brings to mind the 2015 film “Concussion”, starring Will Smith and based on the true story of Dr. Bennett Omalu, who discovered the link between repeated trauma to the head endured by professional football players and brain function degradation.
Susceptibility Weighted Imaging and Quantitative Susceptibility Mapping of the Cerebral Vasculature Using Ferumoxytol
Abstract Purpose—To demonstrate the potential of imaging cerebral arteries and veins with ferumoxytol using susceptibility weighted imaging (SWI) and quantitative susceptibility mapping (QSM). Materials and Methods—The relationships between ferumoxytol concentration...
The Need for Enhanced Imaging Software for TBI
Current imaging technologies are unable to accurately identify the key-biomarkers for traumatic brain injury in a clinically meaningful timeframe. The result can be deadly. Read more from the Wall Street Journal: ...
STrategically Acquired Gradient Echo (STAGE) imaging, part II: Correcting for RF inhomogeneities in estimating T1 and proton density
Abstract Purpose: To develop a method for mapping the B1 transmit (B1t) and B1 receive (B1r) fields from two gradient echo datasets each with a different flip angle and from these two images obtain accurate T1 and proton density (PD) maps of the brain. Methods: A...