STAGE provides a method to visualize brain tissue and neurovascular changes and lesions in the aging brain and Dementia. Phase data is used to reconstruct the source properties…
Aging & Dementia Use Case
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Parkinson’s Disease Use Cases
The STAGE protocol can be used to visualize changes in the Neuromelanin and iron content of key dopaminergic structures such as the Pars Compacta located as part of the Substantia Nigra…
Multiple Sclerosis Use Cases
The STAGE protocol helps to provide brain images which help differentiate Multiple Sclerosis lesion properties. The susceptibility-based STAGE outputs help differentiate normal appearing white matter from those which may have become demyelinated…
Tumor Detection, Metastasis & Radiation Therapy Use Case
STAGE helps to provide a robust collection of contrast outputs which can help further differentiate tumor tissue and the changes occurring in surrounding tissue…
Clinical applications of STAGE published in the journal Magnetic Resonance Imaging
One major thrust in radiology today is image standardization with a focus on rapidly acquired quantitative multi-contrast information. This is critical for multi-center trials, for the collection of big data and for the use of artificial intelligence in evaluating the...
STrategically Acquired Gradient Echo (STAGE) imaging, part I: Creating enhanced T1 contrast and standardized susceptibility weighted imaging and quantitative susceptibility mapping.
Abstract Purpose: To provide whole brain grey matter (GM) to white matter (WM) contrast enhanced T1W (T1WE) images, multi-echo quantitative susceptibility mapping (QSM), proton density (PD) weighted images, T1 maps, PD maps, susceptibility weighted imaging (SWI), and...
Susceptibility Weighted Imaging: Current Status and Future Directions
Abstract Susceptibility weighted imaging (SWI) is a method that uses the intrinsic nature of local magnetic fields to enhance image contrast in order to improve the visibility of various susceptibility sources and to facilitate the diagnostic interpretation. It is...