The STAGE protocol is designed to be highly sensitive to the visualization of lesions that may originate from trauma. STAGE has the ability to demonstrate key vascular brain damage which may be missed by conventional or low resolution scans…
STAGE is designed to benefit imaging and replace standard GRE and SWI in the acute and follow-up setting due to its high sensitivity to blood product lesions in the brain in the form of cerebral microbleeds and thrombus as well as…
Detecting cerebral microbleeds (CMBs) is important in diagnosing a variety of diseases including dementia, stroke and traumatic brain injury. However, manual detection of CMBs can be time-consuming and prone to errors, whereas the current automatic algorithms for CMB detection are usually limited by large number of false positives.
Quantitative MR image processing opens up new avenues of treatment for Traumatic Brain Injury (TBI) in Veterans
For many, the term Traumatic Brain Injury (TBI) brings to mind the 2015 film “Concussion”, starring Will Smith and based on the true story of Dr. Bennett Omalu, who discovered the link between repeated trauma to the head endured by professional football players and brain function degradation.
Cerebral microbleeds (CMBs) are increasingly recognized neuroimaging findings, occurring with cerebrovascular disease, dementia, and aging. This review summarizes the concepts, cause or risk factors, histopathological mechanisms, and clinical consequences of CMBs.
Susceptibility weighted imaging in acute cerebral ischemia: review of emerging technical concepts and clinical applications
Abstract Susceptibility weighted imaging (SWI) is an essential magnetic resonance imaging sequence in the assessment of acute ischemic stroke. In this article, we discuss the physics principals and clinical application of conventional SWI and multi-echo SWI sequences....
Abstract Susceptibility weighted imaging (SWI) is a method that uses the intrinsic nature of local magnetic fields to enhance image contrast in order to improve the visibility of various susceptibility sources and to facilitate the diagnostic interpretation. It is...
Determination of detection sensitivity for cerebral microbleeds using susceptibility- weighted imaging
This study provides a comprehensive analysis of the number of voxels detected in the presence of a CMB on GE magnitude, phase and SWI composite images as a function of resolution, signal‐to‐noise ratio (SNR), TE, field strength and susceptibility using in silico experiments.
Susceptibility-Weighted Imaging is More Reliable Than T2*-Weighted Gradient-Recalled Echo MRI for Detecting Microbleeds
In this study, we investigated the sensitivity and reliability of MRI susceptibility-weighted imaging (SWI) compared with routine MRI T2*-weighted gradient-recalled echo (GRE) for cerebral microbleed (CMB) detection.