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Iron Content in Deep Gray Matter as a Function of Age Using Quantitative Susceptibility Mapping: A Multicenter Study

Iron Content in Deep Gray Matter as a Function of Age Using Quantitative Susceptibility Mapping: A Multicenter Study

The purpose of this study was to evaluate the effect of resolution on iron content using quantitative susceptibility mapping (QSM); to verify the consistency of QSM across field strengths and manufacturers in evaluating the iron content of deep gray matter (DGM) of the human brain using subjects from multiple sites; and to establish a susceptibility baseline as a function of age for each DGM structure using both a global and regional iron analysis.

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Revealing vascular abnormalities and measuring small vessel density in multiple sclerosis lesions using USPIO

Revealing vascular abnormalities and measuring small vessel density in multiple sclerosis lesions using USPIO

In this study, an ultra-small superparamagnetic iron oxide (USPIO) contrast agent, Ferumoxytol, was administered to induce an increase in susceptibility for both arteries and veins to help better reveal the cerebral microvasculature. The purpose of this work was to examine the presence of vascular abnormalities and vascular density in MS lesions using high-resolution susceptibility weighted imaging (SWI).

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Quantifying Tissue Properties of the Optic Radiations Using Strategically Acquired Gradient Echo Imaging and Enhancing the Contrast Using Diamagnetic Susceptibility Weighted Imaging

Quantifying Tissue Properties of the Optic Radiations Using Strategically Acquired Gradient Echo Imaging and Enhancing the Contrast Using Diamagnetic Susceptibility Weighted Imaging

Visualization of the optic radiations is of clinical importance for diagnosing many diseases and depicting their anatomic structures for neurosurgical interventions. In this study, we quantify proton density, T1, T2*, and susceptibility of the optic radiation fiber bundles in a series of 10 healthy control participants using strategically acquired gradient echo imaging.

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Traumatic Brain Injury Use Case

Traumatic Brain Injury Use Case

The STAGE protocol is designed to be highly sensitive to the visualization of lesions that may originate from trauma. STAGE has the ability to demonstrate key vascular brain damage which may be missed by conventional or low resolution scans…

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Stroke Detection Use Case

Stroke Detection Use Case

STAGE is designed to benefit imaging and replace standard GRE and SWI in the acute and follow-up setting due to its high sensitivity to blood product lesions in the brain in the form of cerebral microbleeds and thrombus as well as…

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Aging & Dementia Use Case

Aging & Dementia Use Case

STAGE provides a method to visualize brain tissue and neurovascular changes and lesions in the aging brain and Dementia. Phase data is used to reconstruct the source properties…

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ISNVD’s 2021 Webinar

This January, SpinTech participated in ISNVD's annual global webinar "Approaches and Applications of Multi-Contrast Quantitative Imaging". SpinTech founder, Mark Haacke, PhD, had the opportunity to discuss STAGE in relation to the collection of big data...

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News & Events

All News & Events

SpinTech MRI Presents STAGE at ASNR 2021

SpinTech MRI Presents STAGE at ASNR 2021

SpinTech MRI is excited to debut STAGE, our new MRI software platform that’s pending FDA 510(k) clearance, at ASNR 2021. STAGE provides rapid, quantitative and standardized multi-contrast imaging which can reduce brain MRI acquisition times by over 40%. SpinTech MRI’s...

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We’ll See You at ISMRM 2021!

We’ll See You at ISMRM 2021!

SpinTech is merging innovation and application for novel MRI technologies. Visit us at ISMRM 2021 to see our latest cutting-edge technology advancements. Registration is now open for this year’s virtual ISMRM conference! We’ll be in attendance highlighting STAGE, our...

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